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This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug.
Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical
Produkt Modern CNS Drug Discovery: Reinventing the Treatment of Psychiatric and Neurological Disorders (Schreiber Rudy)(Pevná vazba) má EAN kód 9783030623500.
Kategorie | Knihy |
EAN | 9783030623500 |
This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an
This book overturns the idea that psychiatric drugs work by correcting chemical imbalance and analyzes the professional, commercial and political vested interests that have shaped this view. It provides a comprehensive critique of research on drugs including antidepressants, antipsychotics and mood
This book provides state of the art information on the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic neuromuscular disorders. The opening section discusses the differential diagnosis of acquired myopathies based on clinical, electrophysiological,
Through dozens of tables, illustrative figures, and real-life case examples, established experts in the field, as well as a new generation of scientists, examine clinical concepts; risk factors for and impact of personality disorders; treatment options (including a new chapter on early
Master the diagnosis and effective treatment of veterinary neurologic disorders! de Lahunta's Veterinary Neuroanatomy and Clinical Neurology, 5th Edition provides in-depth coverage of the anatomy, physiology, and pathology of the nervous system. With this knowledge, you will be able to accurately
Master the evaluation and treatment of swallowing disorders Dysphagia: Clinical Management in Adults and Children, 3rd Edition provides the information you need to diagnose and manage dysphagia in patients of all ages. Emphasizing evidence-based practice, this complete resource covers topics from
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This third edition volume expands on the previous editions with new topics that cover drug discovery through translational bioinformatics, informatics, clinical research informatics, as well as clinical
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Preface.- Part 1. Phenotypic features.- Classification of mood disorders. Developmental aspects of depression. Animal models of depression vulnerability. Genetic mouse models of depression.- Part 2. Cellular and Molecular Basis.- The Genetic basis of depression. Neurochemical Imaging and Depressive
Written by experts in geriatric psychiatryIdeal review book to study for the American Board of Psychiatry and Neurology, Geriatric Psychiatry and Neurology initial and re-certification examinations The only text on the market to include a comprehensive, current review of the
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The Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents, based in groundbreaking research from Jill Ehrenreich-May, David H. Barlow, and colleagues, suggest that there may be a simpler and more efficient method of utilizing effective strategies, such
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Loss of the sense of smell or taste is often a sign of neurological disease. Evaluating chemosensation (the senses of smell and taste) during neurological examination can help early detection of neurodegenerative conditions such as Parkinson's and Alzheimer's disease. The importance of such testing
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This volume, the first of the two-volume Drug Delivery Approaches and Nanosystems series, presents a full picture of the state-of-the-art research and development in drug delivery systems using nanotechnology and its applications. It addresses the ever-expanding application of nanotechnology or
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Now completely revised (over 90% new), this definitive practitioner reference and course text comprehensively reviews evidence-based treatments for psychological disorders in children and adolescents. The significantly expanded fourth edition covers an increased number of disorders, as well as
Schizophrenia is one of the most traumatic psychiatric disorders, both for the affected person and their family. It also carries an unfortunate stigma and suffers from frequent misinterpretation by the popular media. The disorder usually manifests itself through significant periods of
Assessment and Treatment of Muscle Imbalance: The Janda Approach blends postural techniques, neurology, and functional capabilities in order to alleviate chronic musculoskeletal pain and promote greater functionality. Developed by Vladimir Janda, respected neurologist and physiotherapist, the
A practical guide to help improve the recognition and treatment of anxiety disorders in primary care. The book details how to recognise an anxiety disorder and make the diagnosis, how to explain it to patients, and to manage it, using simple 10 minute CBT strategies and self-help techniques
A philosophical account of the structure of experience and how it depends on interpersonal relations, developed through a study of auditory verbal hallucinations and thought insertion.In Real Hallucinations, Matthew Ratcliffe offers a philosophical examination of the structure of human experience,