Signaling by Receptor Tyrosine Kinases (Schlessinger Joseph)(Pevná vazba)

Signaling by Receptor Tyrosine Kinases (Schlessinger Joseph)(Pevná vazba)

Signaling by Receptor Tyrosine Kinases (Schlessinger Joseph)(Pevná vazba)

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Signaling by Receptor Tyrosine Kinases (Schlessinger Joseph)(Pevná vazba) - popis produktu

Receptor tyrosine kinases are a large family of cell-surface receptors that respond to a variety of intercellular signals, including insulin, growth factors such as epidermal growth factor (EGF) and fibroblast growth factor (FGF), and molecules involved in neuronal guidance. Ligand bindingstimulates the tyrosine kinase activity of the receptors, leading to recruitment of enzymes and adapter proteins that activate intracellular signaling pathways that control cell proliferation, differentiation, and numerous other biological processes.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology discusses the mechanisms underlying receptor tyrosine kinase signaling, including ligand processing, receptor dimerization, receptor trafficking, and the roles of adapters. The contributorsalso survey the specific functions of the

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